GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs9883753 | chr3:134247231 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.57 | 2.76E-13 | Height |
| BLCA | cis | rs9876781 | 1 | rs9883759 | chr3:48463618 | TREX1 | chr3:48501186-48509043:+ | -0.19 | -3.86 | 0.000134 | Longevity |
| BLCA | cis | rs10935120 | 1 | rs9884031 | chr3:134256500 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.7 | 1.15E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs9884031 | chr3:134256500 | CEP63 | chr3:134204575-134293852:+ | 0.23 | 3.93 | 0.000102 | Height |
| BLCA | cis | rs9902453 | 1 | rs9890205 | chr17:28382704 | EFCAB5 | chr17:28256874-28435469:+ | -0.22 | -3.85 | 0.00014 | Coffee consumption (cups per day) |
| BLCA | cis | rs9902453 | 1 | rs9890886 | chr17:28391076 | EFCAB5 | chr17:28256874-28435469:+ | -0.22 | -3.85 | 0.00014 | Coffee consumption (cups per day) |
| BLCA | cis | rs9902453 | 1 | rs9891871 | chr17:28370191 | EFCAB5 | chr17:28256874-28435469:+ | -0.22 | -3.85 | 0.00014 | Coffee consumption (cups per day) |
| BLCA | cis | rs9910950 | 1 | rs9891968 | chr17:64132846 | AXIN2 | chr17:63524685-63637183:- | 0.56 | 4.92 | 1.3E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs882367 | 1 | rs9892365 | chr17:59491384 | C17orf82 | chr17:59489112-59490641:+ | 0.19 | 4.12 | 4.56E-5 | Sitting height ratio |
| BLCA | cis | rs9894429 | 1 | rs9894429 | chr17:79596811 | TSPAN10 | chr17:79609349-79615778:+ | 0.49 | 8.59 | 2.28E-16 | Eye color traits |
| BLCA | cis | rs9902453 | 1 | rs9896062 | chr17:28357047 | EFCAB5 | chr17:28256874-28435469:+ | -0.23 | -4 | 7.57E-5 | Coffee consumption (cups per day) |
| BLCA | cis | rs9902453 | 1 | rs9902453 | chr17:28349095 | EFCAB5 | chr17:28256874-28435469:+ | -0.23 | -4.1 | 5.11E-5 | Coffee consumption (cups per day) |
| BLCA | cis | rs9910950 | 1 | rs9902706 | chr17:64186988 | AXIN2 | chr17:63524685-63637183:- | 0.53 | 4.5 | 9.15E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs7224737 | 1 | rs9903204 | chr17:40288062 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.56 | 6.82E-6 | Fibrinogen levels |
| BLCA | cis | rs9303401 | 1 | rs9904677 | chr17:56873025 | RAD51C | chr17:56769963-56811690:+ | 0.29 | 5.15 | 4.09E-7 | Cognitive test performance |